This course will cover the chemistry of monosaccharide sugars and glycosides. Viewpoints include chemical constitution, biological function, chemical synthesis and biosynthesis. The following will be developed in detail: basic elements of stereochemistry, structure determination by classical and by spectroscopic means, conformational analysis, biological role (including biosynthetic origins and catabolic processes but excluding systematic, detailed intermediary metabolism), chemical transformations, pharmacological applications, technological, nutritional and environmental aspects, and the use of sugars in chiral synthesis of other natural products.
Carbohydrates-Structure and Biology, J. Lehmann, 1998, Thieme, New York,
ISBN: 3-13-110771-5 (paperback), $49.00.
The Carbohydrates. Chemistry and Biochemistry, (W. Pigman and D. Horton, eds.), 2nd edition, Academic Press, Vols. I and II, 1970 and 1980.
Advances in Carbohydrate Chemistry and Biochemistry, (D. Horton, editor),
Academic Press, Vol. 53 (1998) and earlier volumes in this series. complete
index of articles in all volumes
Carbohydrate Research: An International Journal, (Baker, Defaye, Horton,
Hounsell, eds.), Elsevier. On-line
abstracts of articles and e-mail delivery of tables of contents
This course is open to graduate students and to undergraduate students who have successfully completed organic chemistry.
All Classes will be held on the campus of American University in the Beeghly Chemistry Building
For information on course content or other details, contact Dr. Horton
at 202-885-1767,
or e-mail to Dr. Horton