Kathleen De Cicco-Skinner
Assistant Professor
Department of Biology
- Dr. DeCicco-Skinner's research interests include cancer biology, cell biology, and immunology. Specifically, her research is focused on studying two of the major inflammatory pathways in the cell, MAPK and NF-kB, to identify how these pathways become inappropriately regulated as a normal cell transitions into a cancerous state. Her research uses a variety of immunological and molecular biology techniques in two separate cancer model systems, squamous cell carcinoma and multiple myeloma.
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Degrees
PhD, Nutritional Immunology, Pennsylvania State University, University Park
BS, Biochemistry, Virginia Polytechnic Institute & State University
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OFFICE
- CAS - Biology
- Hurst - 112C
FOR THE MEDIA
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at 202-885-5950 or submit a request.
SEE ALSO
- Biology Department
Teaching
Fall 2013
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- BIO-300 Cell Biology With Laboratory
- Description
Scholarly, Creative & Professional Activities
Grants and Sponsored Research
- 2011 NIH R15 AREA Grant, $390,000 pending
- 2011 American University Faculty Research Award, $10,000
- 2008 American University Mellon Grant, $2000
- 2001 Post Doctoral Fellowship - NIH
- 1999 Society for Experimental Biology and Medicine (SEBM) Travel Grant
- 1997 Recipient of Paul E. Hand and Uni-Marts, Inc. Travel Grant
- 1996 Recipient of Graduate Program in Nutrition Competitive Research Award
- 1995 Awarded Outstanding Biochemist for Graduating Class (Virginia Tech)
- 1994-1995 John Pratt Animal Nutrition Senior Research Scholarship
- 1991 John Pratt Freshman Scholarship
Selected Publications
- DeCicco-Skinner, KL, Trovato, EL, Simmons, JK, Lepage, PK, Wiest, J. (2010) Loss of Tumor Progression Locus 2 (TPL2) enhances tumorigenesis and inflammation in two-stage skin carcinoigenesis.  Oncogene. 2010 Oct 11. [Epub ahead of print]
- Jacobs, S., Lie, DC., DeCicco, KL, Shi, Y., De Luca, L., Gage, FH., Evans, RM (2006) Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proc. Natl. Acad. Sci.  103: 3902-7.
- DeCicco, KL., Tanaka, T., Andreola, F., De Luca, LM (2004) The effect of thalidomide on non-small cell lung cancer (NSCLC) cell lines: Possible mediation through PPAR- g . Carcinogenesis.25:1805-12.
- DeCicco, KL., Youngdahl, JD, Ross, AC (2001) All-trans-retinoic acid and polyriboinosinic:polyribocytidylic acid in combination potentiate specific antibody production and cell-mediated immunity in Lewis rats. Immunology. 104(3): 341-8.
- DeCicco, KL. Zolfaghari, R., Li, N-Q, Ross, AC (2000) Retinoic acid and Polyriboinosinic: Polyribocytidylic acid act synergistically to enhance the antibody response to tetanus toxoid during vitamin A deficiency: Possible involvement of Interleukin-2 receptor b , Signal Transducer and Activator of Transcription-1, and Interferon Regulatory Factor-1. J. Infectious Disease . 182 Suppl 1: S29-S36.
- DeCicco, KL and AC Ross (2000) All-trans-retinoic acid and polyriboinosinic: polyribocytidylic acid cooperate to elevate anti-tetanus immunoglobulin G and immunoglobulin M responses in vitamin A-deficient Lewis rats and Balb/c mice.Proc. Nutr. Society 59: 1-11.
- Dawson , HD., Li, N-Q., DeCicco, KL., Nibert, JA., and Ross, AC. (1999) Chronic marginal vitamin A status reduces natural killer cell function in aging Lewis rats. J. Nutrition. 129: 1510.
Media Appearances
“Genetic Tests Coming To A Drugstore Near You”, WAMA 88.5, 2010
Executive Experience
- (2003-Present) Assistant Professor, Department of Biology, American University
- (2001-2004) Cancer Research Training Award Postdoctoral Fellow
AU News and Achievements
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Researching the Way to a Cure
Professor Katie DeCicco-Skinner wins NIH grant to investigate why lack of a gene causes skin cancer ...
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