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Psychopharmacology | Lab Members

Maria Briscione

mb5094a@student.american.edu

Curriculum Vitae


I'm currently a senior at American University studying biochemistry and psychology. My research focuses on the underlying mechanism of the aversive effects of cocaine, as indexed by conditioned taste aversion learning. Currently, I'm examining the effects of serotonin receptor antagonism on cocaine-induced taste aversions, as a method for determining serotonin's possible role in mediating cocaine's underlying aversive mechanism. My previous research consists of assessing the effects of selective antagonists for dopamine on cocaine-induced aversions and investigating the effects of dopamine inhibition on cocaine-induced aversions using the cross-drug preexposure procedure. I'm also interested in seeing if transgenic manipulations, pharmacological antagonism and cross-drug preexposure preparations result in similar findings regarding the mechanism underlying cocaine's aversive effects. Concurrent findings would lead to confirming the purity of the assay as well as confirmation of the underlying mechanism.

PUBLICATIONS

Briscione, MA, Serafine, KM, Merluzzi, AP, Rice, KC, Riley, AL. The assessment of 5-HT3 receptor antagonism on cocaine-induced conditioned taste aversions in preparation.

Serafine, KM, Briscione, MA, Rice, KC, Riley, AL. Dopamine mediates cocaine-induced conditioned taste aversions as demonstrated with cross-drug preexposure to GBR 12909. Pharmacol Biochem Behav, 2012;102:269-274. [PDF] 

Serafine, KM, Briscione, MA, Riley AL. The effects of haloperidol on cocaine-induced conditioned taste aversions. Physiol Behav, 2012;105:1161-7. [PDF]

CONFERENCE PRESENTATIONS

Poster Presentations

Serafine, KM, Briscione, MA, Rice, KC, and Riley, AL. (2012, June) The assessment of dopaminergic involvement in cocaine-induced conditioned taste aversions. Poster presented at the annual meeting of the College on Problems of Drug Dependence, Palm Springs, CA.

Briscione, MA, Serafine, KM, Rice, KC, and Riley, AL. (2012, April). The assessment of dopaminergic involvement in cocaine-induced conditioned taste aversions. Poster presented at the 10th Annual Georgetown University Undergraduate Research Conference, Washington, DC.

Serafine, KM, Briscione, MA, Rice, KC, and Riley, AL. (2012, April) The assessment of dopaminergic involvement in cocaine-induced conditioned taste aversions. Poster presented at the annual meeting of the American Society for Pharmacology and Experimental Therapeutics, San Diego, CA.

Briscione, MA, Serafine, KM, Rice, KC, and Riley, AL. (2012, March). The assessment of dopaminergic involvement in cocaine-induced conditioned taste aversions. Poster presented at the 22nd Annual Robyn Rafferty Mathias Student Research Conference, Washington, DC.

Serafine, KM, Briscione, MA, Rice, KC, and Riley, AL. (2011, November). The assessment of dopaminergic involvement in cocaine-induced conditioned taste aversions. Poster presented at the annual meeting of The Society for Stimulus Properties of Drugs, Washington, DC.

Serafine, KM, Briscione, MA, Rice, KC, Hall, FS, Uhl, GR, and Riley, AL. (2011, August). The role of monoamines in cocaine-induced conditioned taste aversions. Poster presented at the NIH Summer Research Program Poster Day, Bethesda, MD.

Briscione, MA, Serafine, KM, Rice, KC, and Riley, AL. (2011, April). Effects of cross-drug preexposure on vanoxerine- and cocaine-induced conditioned taste aversions. Poster presented at the 21st Annual Robyn Rafferty Mathias Student Research Conference, Washington, DC.

Maria Briscione