Kathleen De Cicco-Skinner
Department of Biology
- Dr. DeCicco-Skinner's research interests include cancer biology, cell biology, and immunology. Specifically, her research is focused on studying two of the major inflammatory pathways in the cell, MAPK and NF-kB, to identify how these pathways become inappropriately regulated as a normal cell transitions into a cancerous state. Her research uses a variety of immunological and molecular biology techniques in two separate cancer model systems, squamous cell carcinoma and multiple myeloma.
DegreesPhD, Nutritional Immunology, Pennsylvania State University, University Park
BS, Biochemistry, Virginia Polytechnic Institute & State University
Scholarly, Creative & Professional Activities
Grants and Sponsored Research
- 2011 NIH R15 AREA Grant, $390,000 pending
- 2011 American University Faculty Research Award, $10,000
- 2008 American University Mellon Grant, $2000
- 2001 Post Doctoral Fellowship - NIH
- 1999 Society for Experimental Biology and Medicine (SEBM) Travel Grant
- 1997 Recipient of Paul E. Hand and Uni-Marts, Inc. Travel Grant
- 1996 Recipient of Graduate Program in Nutrition Competitive Research Award
- 1995 Awarded Outstanding Biochemist for Graduating Class (Virginia Tech)
- 1994-1995 John Pratt Animal Nutrition Senior Research Scholarship
- 1991 John Pratt Freshman Scholarship
- DeCicco-Skinner, KL, Trovato, EL, Simmons, JK, Lepage, PK, Wiest, J. (2010) Loss of Tumor Progression Locus 2 (TPL2) enhances tumorigenesis and inflammation in two-stage skin carcinoigenesis.&nbsp; Oncogene. 2010 Oct 11. [Epub ahead of print]
- Jacobs, S., Lie, DC., DeCicco, KL, Shi, Y., De Luca, L., Gage, FH., Evans, RM (2006) Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proc. Natl. Acad. Sci.&amp;nbsp; 103: 3902-7.
- DeCicco, KL., Tanaka, T., Andreola, F., De Luca, LM (2004) The effect of thalidomide on non-small cell lung cancer (NSCLC) cell lines: Possible mediation through PPAR- g . Carcinogenesis.25:1805-12.
- DeCicco, KL., Youngdahl, JD, Ross, AC (2001) All-trans-retinoic acid and polyriboinosinic:polyribocytidylic acid in combination potentiate specific antibody production and cell-mediated immunity in Lewis rats. Immunology. 104(3): 341-8.
- DeCicco, KL. Zolfaghari, R., Li, N-Q, Ross, AC (2000) Retinoic acid and Polyriboinosinic: Polyribocytidylic acid act synergistically to enhance the antibody response to tetanus toxoid during vitamin A deficiency: Possible involvement of Interleukin-2 receptor b , Signal Transducer and Activator of Transcription-1, and Interferon Regulatory Factor-1. J. Infectious Disease . 182 Suppl 1: S29-S36.
- DeCicco, KL and AC Ross (2000) All-trans-retinoic acid and polyriboinosinic: polyribocytidylic acid cooperate to elevate anti-tetanus immunoglobulin G and immunoglobulin M responses in vitamin A-deficient Lewis rats and Balb/c mice.Proc. Nutr. Society 59: 1-11.
- Dawson , HD., Li, N-Q., DeCicco, KL., Nibert, JA., and Ross, AC. (1999) Chronic marginal vitamin A status reduces natural killer cell function in aging Lewis rats. J. Nutrition. 129: 1510.
“Genetic Tests Coming To A Drugstore Near You”, WAMA 88.5, 2010
- (2003-Present) Assistant Professor, Department of Biology, American University
- (2001-2004) Cancer Research Training Award Postdoctoral Fellow