Katie DeCicco-Skinner

Associate Professor
Department of Biology

  • Dr. DeCicco-Skinner's research interests include cancer biology, cell biology, and immunology. Specifically, her research is focused on studying two of the major inflammatory pathways in the cell, MAPK and NF-kB, to identify how these pathways become inappropriately regulated as a normal cell transitions into a cancerous state. Her research uses a variety of immunological and molecular biology techniques in two separate cancer model systems, squamous cell carcinoma and multiple myeloma.
  • Degrees

    PhD, Nutritional Immunology, Pennsylvania State University, University Park
    BS, Biochemistry, Virginia Polytechnic Institute & State University

  • CAS - Biology
  • Hurst - 112C

  • (202) 885-2193 (Office)
  • (202) 885-2182 (Fax)
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Scholarly, Creative & Professional Activities

Grants and Sponsored Research

  • 2011 NIH R15 AREA Grant, $390,000 pending 
  • 2011 American University Faculty Research Award, $10,000   
  • 2008 American University Mellon Grant, $2000   
  • 2001 Post Doctoral Fellowship - NIH
  • 1999 Society for Experimental Biology and Medicine (SEBM) Travel Grant  
  • 1997 Recipient of Paul E. Hand and Uni-Marts, Inc. Travel Grant  
  • 1996 Recipient of Graduate Program in Nutrition Competitive Research Award
  • 1995 Awarded Outstanding Biochemist for Graduating Class (Virginia Tech)
  • 1994-1995 John Pratt Animal Nutrition Senior Research Scholarship
  • 1991 John Pratt Freshman Scholarship

Selected Publications

  • DeCicco-Skinner, KL, Trovato, EL, Simmons, JK, Lepage, PK, Wiest, J. (2010) Loss of Tumor Progression Locus 2 (TPL2) enhances tumorigenesis and inflammation in two-stage skin carcinoigenesis.  Oncogene. 2010 Oct 11. [Epub ahead of print]
  • Jacobs, S., Lie, DC., DeCicco, KL, Shi, Y., De Luca, L., Gage, FH., Evans, RM (2006) Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proc. Natl. Acad. Sci.  103: 3902-7.
  • DeCicco, KL., Tanaka, T., Andreola, F., De Luca, LM (2004) The effect of thalidomide on non-small cell lung cancer (NSCLC) cell lines: Possible mediation through PPAR- g . Carcinogenesis.25:1805-12.
  • DeCicco, KL., Youngdahl, JD, Ross, AC (2001) All-trans-retinoic acid and polyriboinosinic:polyribocytidylic acid in combination potentiate specific antibody production and cell-mediated immunity in Lewis rats. Immunology. 104(3): 341-8.
  • DeCicco, KL. Zolfaghari, R., Li, N-Q, Ross, AC (2000) Retinoic acid and Polyriboinosinic: Polyribocytidylic acid act synergistically to enhance the antibody response to tetanus toxoid during vitamin A deficiency: Possible involvement of Interleukin-2 receptor b , Signal Transducer and Activator of Transcription-1, and Interferon Regulatory Factor-1. J. Infectious Disease . 182 Suppl 1: S29-S36.
  • DeCicco, KL and AC Ross (2000) All-trans-retinoic acid and polyriboinosinic: polyribocytidylic acid cooperate to elevate anti-tetanus immunoglobulin G and immunoglobulin M responses in vitamin A-deficient Lewis rats and Balb/c mice.Proc. Nutr. Society 59: 1-11. 
  • Dawson , HD., Li, N-Q., DeCicco, KL., Nibert, JA., and Ross, AC. (1999) Chronic marginal vitamin A status reduces natural killer cell function in aging Lewis rats. J. Nutrition. 129: 1510.

Media Appearances

“Genetic Tests Coming To A Drugstore Near You”,  WAMA 88.5, 2010

Executive Experience

  • (2003-Present) Assistant Professor, Department of Biology, American University
  • (2001-2004) Cancer Research Training Award Postdoctoral Fellow

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